Eight healthy female adult camels were used to study the effect of long term dehydrntion on serum constituents in extreme climatic conditions viz. cold lind hot. The dehydration phases were of 24 dllys in cold and 13 dnys in hot conditions. The changes in sodium, potassium, calcium and phosphorus were non significllnt (P> 0.05) while in chloride, glucose, total proteins, urea, bilirubin. cholesterol and creatinine were significant (P~ O. 05l during dehydration phase. The mean values of all the constituents tended to return to normnl as the rehydration phase advanced. Changes in sodium and potassium in dehydrated camels reOected thllt they were able to maintain the salt bnlance.