Effect of melatonin on torsion and reperfusion induced pathogenesis of rat uterus
We investigated the use of melatonin to improve fertility and reduce uterine damage caused
by torsion of the uterus in pregnant rats. We used 35 pregnant rats at gestational age 18
days. The animals were randomized into five groups. Group 1 was anesthetized only. Group
2 was subjected to experimental uterine torsion of 360° and the torsion was corrected after 6
h. Group 3 was subjected to uterine torsion of 360°, the torsion was corrected after 6 h and
melatonin was administered at the time of correction. Group 4 rats were subjected to 360º …
by torsion of the uterus in pregnant rats. We used 35 pregnant rats at gestational age 18
days. The animals were randomized into five groups. Group 1 was anesthetized only. Group
2 was subjected to experimental uterine torsion of 360° and the torsion was corrected after 6
h. Group 3 was subjected to uterine torsion of 360°, the torsion was corrected after 6 h and
melatonin was administered at the time of correction. Group 4 rats were subjected to 360º …
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