Effect of morphine and ibuprofen on nociceptive behavior, preening and motor activity following tonic chemical pain in the Japanese quail (Coturnix japonica)
E Khalilzadeh, S Mousavi, M Dolatyarieslami… - Veterinary Anaesthesia …, 2022 - Elsevier
Objective To establish a tonic chemical model of pain in quail and evaluate the efficacy of
opioid and non-steroidal anti-inflammatory drugs. Study design A randomized, blinded,
experimental study design. Animals A total of 120 male Japanese quail, aged 7 weeks.
Methods A formalin solution (0.3%, 0.6% and 0.9%; total volume of 40 μL) was injected
subcutaneously (SC) into the medial aspect of the right metatarsus (shank). Foot lift and
preening activities were recorded for 45 minutes following injection of formalin and scored …
opioid and non-steroidal anti-inflammatory drugs. Study design A randomized, blinded,
experimental study design. Animals A total of 120 male Japanese quail, aged 7 weeks.
Methods A formalin solution (0.3%, 0.6% and 0.9%; total volume of 40 μL) was injected
subcutaneously (SC) into the medial aspect of the right metatarsus (shank). Foot lift and
preening activities were recorded for 45 minutes following injection of formalin and scored …