Biosynthesis of its active ingredients, the ganoderic acids (GAs), together with signal
transduction related to the fungal biology of G. lucidum, are critical for this application.
However, regulation of G. lucidum GA biosynthesis and signal transduction remains
enigmatic. We investigated the role of reactive oxygen species (ROS) on biosynthesis of
individual GAs and on MAPK (mitogen-activated protein kinase) signaling. Antioxidant …