Effects of Hyosine N-butyl bromide on the detection of polyps during colonoscopy.
JM Lee, JH Cheon, JJ Park, CM Moon… - Hepato …, 2010 - europepmc.org
JM Lee, JH Cheon, JJ Park, CM Moon, ES Kim, TI Kim, WH Kim
Hepato-gastroenterology, 2010•europepmc.orgResults The number of patients with decrease in spasm score of 0, 1, and 2 between
insertion and withdrawal were 5 (8.6%), 31 (53.4%), and 22 (37.9%) in the Hyosine group,
and 10 (17.2%), 46 (79.3%), and 2 (3.4%) in the Placebo group, respectively (p< 0.001). In
patients with spasm score> or= 3 during insertion, more polyps per patient were likely to be
detected in the Hyoscine group than the Placebo group (1.21+/-2.23 vs. 0.41+/-0.91; p=
0.060). Conclusions Our study suggests that hyosine might increase the detection rate of …
insertion and withdrawal were 5 (8.6%), 31 (53.4%), and 22 (37.9%) in the Hyosine group,
and 10 (17.2%), 46 (79.3%), and 2 (3.4%) in the Placebo group, respectively (p< 0.001). In
patients with spasm score> or= 3 during insertion, more polyps per patient were likely to be
detected in the Hyoscine group than the Placebo group (1.21+/-2.23 vs. 0.41+/-0.91; p=
0.060). Conclusions Our study suggests that hyosine might increase the detection rate of …
Results
The number of patients with decrease in spasm score of 0, 1, and 2 between insertion and withdrawal were 5 (8.6%), 31 (53.4%), and 22 (37.9%) in the Hyosine group, and 10 (17.2%), 46 (79.3%), and 2 (3.4%) in the Placebo group, respectively (p< 0.001). In patients with spasm score> or= 3 during insertion, more polyps per patient were likely to be detected in the Hyoscine group than the Placebo group (1.21+/-2.23 vs. 0.41+/-0.91; p= 0.060).
Conclusions
Our study suggests that hyosine might increase the detection rate of polyps in patients with moderate to marked degree of colonic spasm during colonoscope insertion. Further large scale studies are needed to validate our observations.
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