[HTML][HTML] Effects of atorvastatin on the hypertension-induced oxidative stress in the rat brain

MT Mohammadi, R Amini, Z Jahanbakhsh… - Iranian biomedical …, 2013 - ncbi.nlm.nih.gov
Background: It is well known that the development of brain oxidative stress is one of the most
serious complications of arterial hypertension that evokes brain tissue damage. The aim of
this study was to examine the effects of atorvastatin treatment (20 mg/kg/day), as an
antioxidant, to prevent the brain tissue oxidative stress in the hypertensive (HTN) rats.
Methods: Experiments were performed in four groups of rats (n= 5 each group): sham, sham-
treated, HTN and HTN treated. Rats were made HTN by aortic constriction above the renal …

Effects of atorvastatin on the hypertension-induced oxidative stress in the rat brain

A Reza, J Zahra, S Shahnaz - 2013 - pesquisa.bvsalud.org
It is well known that the development of brain oxidative stress is one of the most serious
complications of arterial hypertension that evokes brain tissue damage. The aim of this study
was to examine the effects of atorvastatin treatment [20 mg/kg/day], as an antioxidant, to
prevent the brain tissue oxidative stress in the hypertensive [HTN] rats. Experiments were
performed in four groups of rats [n= 5 each group] sham, sham-treated, HTN and HTN
treated. Rats were made HTN by aortic constriction above the renal arteries. After 30 days …
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