Effects of cyclopiazonic acid, a novel Ca2+‐ATPase inhibitor, on contractile responses in skinned ileal smooth muscle
Y Uyama, Y Imaizumi… - British journal of …, 1992 - Wiley Online Library
1 Effects of cyclopiazonic acid (CPA), a specific inhibitor of the Ca2+‐ATPase in
sarcoplasmic reticulum (SR) of skeletal and cardiac muscles, on contractile responses
induced by Ca2+‐release from intracellular storage sites were examined in the longitudinal
smooth muscle strip of the guinea‐pig ileum skinned with β‐escin. 2 Ca2+‐loading of
storage sites (Ca2+‐uptake) was performed in pCa 6.3 solution. The amount of Ca2+ taken
up was monitored by use of the amplitude of contraction following application of 25 mm …
sarcoplasmic reticulum (SR) of skeletal and cardiac muscles, on contractile responses
induced by Ca2+‐release from intracellular storage sites were examined in the longitudinal
smooth muscle strip of the guinea‐pig ileum skinned with β‐escin. 2 Ca2+‐loading of
storage sites (Ca2+‐uptake) was performed in pCa 6.3 solution. The amount of Ca2+ taken
up was monitored by use of the amplitude of contraction following application of 25 mm …
[引用][C] Effects of cyclopiazonic acid, a novel Ca (2+)-ATPase inhibitor, on contractile responses and an outward current in smooth muscle
Y Imaizumi, M Suzuki, Y Uyama… - Japanese journal …, 1992 - pubmed.ncbi.nlm.nih.gov
… Muscle Contraction / drug effects … Calcium-Transporting ATPases cyclopiazonic acid …
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