Effects of poly-N-acetyl glucosamine (pGlcNAc) patch on wound healing in db/db mouse

G Pietramaggiori, HJ Yang, SS Scherer… - Journal of Trauma …, 2008 - journals.lww.com
Background: Poly-N-acetyl glucosamine (pGlcNAc) nanofiber-based materials, produced by
a marine microalga, have been characterized as effective hemostatic agents. In this study,
we hypothesized that a pGlcNAc fiber patch may enhance wound healing in the db/db
mouse. Methods: pGlcNAc patches were applied on 1-cm 2, full-thickness, skin wounds in
the db/db mouse model. Wounds (n= 15 per group) were dressed with a pGlcNAc nanofiber
patch for 1 hour, 24 hours, or left untreated. After the application time, patches were removed …

Effects of Poly-N-acetyl Glucosamine (pGlcNAc) Patch on Wound Healing in db/db Mouse

HJ Yang, CS Yoon - Archives of Plastic Surgery, 2008 - koreascience.kr
Purpose: Poly-N-acetyl glucosamine (PGlcNAc) nanofiber-based materials, produced by a
marine microalga, have been characterized as effective hemostatic and angiogenic agents.
The similarity between PGlcNAc patch and the natural extracellular matrix allows it to
support new healthy tissue growth in an injured area and to encourage fluid absorption. In
this study, we hypothesized that a poly-N-acetyl glucosamine fiber patch (PGlcNAc patch)
may enhance wound healing in the db/db mouse. Methods: PGlcNAc patches were applied …
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