Electrochemical methoxymethylation of alcohols–a new, green and safe approach for the preparation of MOM ethers and other acetals

X Luo, X Ma, F Lebreux, IE Markó, K Lam - Chemical Communications, 2018 - pubs.rsc.org
X Luo, X Ma, F Lebreux, IE Markó, K Lam
Chemical Communications, 2018pubs.rsc.org
… A new, green, safe, cost-effective and highly efficient electrochemical approach for the
methoxymethylation of alcohols and phenols was successfully developed. The methodology was
also applied to the synthesis of substituted acetals. … or the commercially available Electrasyn
2.0, we have developed a new, environmentally friendly, safe and cost-effective electrochemical
methoxymethylation methodology that does not rely on the use of the carcinogenic MOMCl.
The desired MOM ethers were obtained in high yields without requiring any purification, and …
A new, green, safe, cost-effective and highly efficient electrochemical approach for the methoxymethylation of alcohols and phenols was successfully developed. The methodology was also applied to the synthesis of substituted acetals.
The Royal Society of Chemistry