[引用][C] Elucidation of the antimicrobial capabilities of spirooxindole fused heterocycles synthesized via catalyst free method

T Preeti Prasad, D Magoo, K Meena, SM Ghorai… - Indian J. Nat. Sci, 2020

[PDF][PDF] Elucidation of the Antimicrobial Capabilities of Spirooxindole Fused Heterocycles Synthesized Via Catalyst Free Method

H Kaur - researchgate.net
In this study, catalyst free synthesis of isoxazolo [5, 4-b] pyridine/quinoline derivatives via
one-pot threecomponent condensation, was replicated by using the previously reported
components (isatins, 3-methylisoxazol-5-amine and cyclic enolizable carbonyl compounds
in ethylene glycol at 80oC. Microbicidal activitiesof the 16 spirooxindole derivatives (SD)
were evaluated against both bacterial (E. coli) and fungal (C. albicans) pathogens, wherein
it was found that the derivatives showed better antifungal activity as compared to …
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