Emerging immune targets for the treatment of multiple myeloma

A Sohail, A Mushtaq, A Iftikhar, Z Warraich… - …, 2018 - Taylor & Francis
… We reviewed emerging immune strategies for multiple myeloma (MM) therapy excluding
US FDA approved drugs. In relapsed refractory MM, isatuximab (anti-CD38) monotherapy …

Multiple myeloma therapy: emerging trends and challenges

D Dima, D Jiang, DJ Singh, M Hasipek, HS Shah… - Cancers, 2022 - mdpi.com
new therapeutic approaches. In this review we discuss the current treatment paradigm of
multiple myeloma … therapeutic potential of emerging preclinical research in multiple myeloma. …

Emerging options in multiple myeloma: targeted, immune, and epigenetic therapies

S Kumar - Hematology 2014, the American Society of …, 2017 - ashpublications.org
… tremendous progress in terms of new therapies for multiple myeloma (MM), paralleled by a
… effort to identify new therapeutic targets in MM. Broadly, the therapeutic targets in MM can be …

Restoring natural killer cell immunity against multiple myeloma in the era of new drugs

G Pittari, L Vago, M Festuccia, C Bonini… - Frontiers in …, 2017 - frontiersin.org
… It has been associated with resistance to newnew therapeutic strategies to overcome
resistance to current therapies. MM is also characterized by a gradual and progressive immune

Current and emerging immunotherapeutic approaches to the treatment of multiple myeloma

D Swan, K Lynch, M Gurney… - Therapeutic advances …, 2019 - journals.sagepub.com
… of the immune system in myeloma is becoming increasingly understood. Therapies targeting
the immunological components of myeloma … Furthermore, evidence suggests that immune

Emerging immunotherapies in multiple myeloma

UA Shah, S Mailankody - Bmj, 2020 - bmj.com
Multiple myeloma is characterized by progressive immune … imide drug, in the treatment of
multiple myeloma in 1997 and its … started an era of new drug approvals for myeloma including …

New strategies in the treatment of multiple myeloma

NC Munshi, KC Anderson - Clinical cancer research, 2013 - AACR
… approaches are being evaluated to treat multiple myeloma. An emerging focus has been
to augment autologous anti–multiple myeloma immune responses using both dendritic cell–…

Targeting the immune niche within the bone marrow microenvironment: the rise of immunotherapy in multiple myeloma

K Podar, D Jager - Current cancer drug targets, 2017 - ingentaconnect.com
… genes represent yet another therapeutic target in the MM to enhance immune cell activity.
While this review summarizes up-to-date knowledge on emerging mAbs and their therapeutic …

Emerging therapies in Multiple Myeloma: Leveraging immune checkpoint inhibitors for improved outcomes

AA Mandavkar, SSN Padakanti, S Gupta… - Human …, 2025 - journals.sagepub.com
… summary of the Multiple Myeloma microenvironment, and emerging revolutionary therapeutic
… therapy to improve the quality of life for Multiple Myeloma patients. Emerging approaches: …

[HTML][HTML] Toll-like receptors: New targets for multiple myeloma treatment?

O Akesolo, B Buey, M Beltrán-Visiedo… - Biochemical …, 2022 - Elsevier
… in treating multiple myeloma, this disease still remains incurable. Toll-like receptors (TLRs)
are key immune … In multiple myeloma there is a dysregulated signalling of TLRs due to an …