Epigenetics is a broad term used to encompass changes in gene expression which are not
associated with any changes in the DNA sequence. They are important for normal
homeostasis of the cell. From a clinical perspective, aberrant epigenetic changes may play
more important roles in the pathophysiology of cancers, including breast cancer. In addition
to mutations, breast cancer is also induced by epigenetic changes, notably aberrant DNA
methylation, chromatin modifications, and gene expression dysregulation by non-coding …