Continued advancements in sequencing technologies have fueled the development of new
sequencing applications and promise to flood current databases with raw data. A number of
factors prevent the seamless and easy use of these data, including the breadth of project
goals, the wide array of tools that individually perform fractions of any given analysis, the
large number of associated software/hardware dependencies, and the detailed expertise
required to perform these analyses. To address these issues, we have developed an …

EDGE bioinformatics was developed to help biologists process Next Generation
Sequencing data (in the form of raw FASTQ files), even if they have little to no bioinformatics
expertise. EDGE is a highly integrated and interactive web-based platform that is capable of
running many of the standard analyses that biologists require for viral, bacterial/archaeal,
and metagenomic samples. EDGE provides the following analytical workflows: quality
trimming and host removal, assembly and annotation, comparisons against known …