Enantioselective synthesis of (-)-zeylena from styrene

T Hudlicky, G Seoane, T Pettus - The Journal of Organic …, 1989 - ACS Publications
X/'-Nu inactive in the P-388 lymphocytic leukemia screen, 6 its relationship to the active
cyclohexene oxides was estab-lished and several syntheses of these interesting com-
pounds were reported. 7 The biogenesis of zeylena and other cyclohexene oxides has been
suggested to take place in higher organisms through the nucleophilic opening of arene
oxides 2 generated by the enzymatic oxygenation of benzyl benzoate as shown in eq 1,
Scheme I. 3 All known cyclohexene oxides can be derived by further manipulations of trans …

[引用][C] ENANTIOSELECTIVE SYNTHESIS OF (-)-ZEYLENA FROM STYRENE

G Seoane, T Pettus, T Hudlicky - 1989 - hero.epa.gov
ENANTIOSELECTIVE SYNTHESIS OF (-)-ZEYLENA FROM STYRENE | Health &
Environmental Research Online (HERO) | US EPA … ENANTIOSELECTIVE SYNTHESIS
OF (-)-ZEYLENA FROM STYRENE
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