Endothelial signaling during development

O Cleaver, DA Melton - Nature medicine, 2003 - nature.com
… This review will examine the potential role of endothelial paracrine signals during
organogenesis and cell differentiation, with consideration given to the ramifications of endothelial

VEGF signaling inside vascular endothelial cells and beyond

A Eichmann, M Simons - Current opinion in cell biology, 2012 - Elsevier
… events of VEGFR signaling occur inside the endothelial cell and are … signaling is increasingly
recognized for its roles outside of the vascular system, notably during neural development, …

Heart valve development: endothelial cell signaling and differentiation

EJ Armstrong, J Bischoff - Circulation research, 2004 - Am Heart Assoc
… physiologic steps that occur during the process of cardiac cushion development. Therefore,
during development, with an emphasis on potential points of interaction between signaling

Endothelial-mural cell signaling in vascular development and angiogenesis

K Gaengel, G Genové, A Armulik… - … , and vascular biology, 2009 - Am Heart Assoc
During vascular development endothelial cells express Cx43 and mural cells Cx43 and
Cx45. Genetic ablation of Cx45 causes defects reminiscent of Alk5 and other TGF-β pathway …

Signaling pathways induced by vascular endothelial growth factor

B Larrivee, A Karsan - International journal of …, 2000 - spandidos-publications.com
endothelial growth factor (VEGF) family members are major mediators of vasculogenesis
and angiogenesis both during development … the ability to promote endothelial cell viability, …

Endothelial‐to‐mesenchymal transition in cardiovascular diseases: developmental signaling pathways gone awry

G Sánchez‐Duffhues… - Developmental …, 2018 - Wiley Online Library
endothelial-specific protein at one moment during their life time. This has enormously
facilitated the identification of EndMT-derived cells, because mesenchymal cells usually down-…

A role for thrombin receptor signaling in endothelial cells during embryonic development

CT Griffin, Y Srinivasan, YW Zheng, W Huang… - Science, 2001 - science.org
… Our results are equally consistent with models in which the coagulation cascade and
endothelial PAR1 signaling contribute to vascular development and integrity in ways unrelated to …

Endothelial development taking shape

A Wacker, H Gerhardt - Current opinion in cell biology, 2011 - Elsevier
… membrane protrusion at the leading edge and RhoA controlling contractility at the trailing
edge, many evidences support a more complicated picture of Rho GTPases signaling during

Vascular endothelial growth factor signaling pathways: therapeutic perspective

M Kowanetz, N Ferrara - Clinical Cancer Research, 2006 - AACR
… The establishment of a vascular supply is one of the earliest and most important events
occurring during embryonic development. Growth and maturation of a functional vascular …

Signaling hierarchy regulating human endothelial cell development

MA Kelly, KK Hirschi - Arteriosclerosis, thrombosis, and vascular …, 2009 - Am Heart Assoc
endothelial-specific genes and proteins. Our finding that Ihh signaling plays a role in mediating
human endothelial cell … Because during murine vasculogenesis in vivo such endoderm-…