Enhanced predictive power of quantitative TWA during routine exercise testing in the Finnish Cardiovascular Study

M Minkkinen, M Kähönen, J Viik, K Nikus… - Journal of …, 2009 - Wiley Online Library
Introduction: We examined whether quantification of T‐wave alternans (TWA) enhances this
parameter's capacity to evaluate the risk for total and cardiovascular mortality and sudden
cardiac death (SCD). Methods and Results: The Finnish Cardiovascular Study (FINCAVAS)
enrolled consecutive patients (n= 2,119; 1,342 men and 777 women) with a clinically
indicated exercise test with bicycle ergometer. TWA (time domain‐modified moving average
method) was analyzed from precordial leads, and the results were grouped in increments of …

[PDF][PDF] Enhanced Predictive Power of Quantitative TWA During Routine Exercise Testing in the Finnish Cardiovascular Study

K NIKUS, TL AKI, R LEHTINEN, TKO OBI… - 2008 - academia.edu
Methods and Results: The Finnish Cardiovascular Study (FINCAVAS) enrolled consecutive
patients (n= 2,119; 1,342 men and 777 women) with a clinically indicated exercise test with
bicycle ergometer. TWA (time domain-modified moving average method) was analyzed from
precordial leads, and the results were grouped in increments of 10 µV. Hazard ratios (HR)
for total and cardiovascular mortality and SCD were estimated for preexercise, routine
exercise, and postexercise stages. Cox regression analysis was performed. During follow …
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