In this work we propose a methodological risk and resilience framework to assess comprehensively multiple climate risks and related natural hazards, such as floods, forest fires, and droughts, for interconnected Critical Infrastructures (CI). As vital components of the normal functioning of modern societies, their resilience encompasses the operational elements, their structural integrity and the capacity to maximize business output under climate stressors. Critical infrastructures are commonly designed, built and maintained based on rigorous standards in order to withstand the climate and weather-related pressures, but shifts in climate characteristics may result in increases of the magnitude and frequency of potential risks, or expose specific CI to new risks not previously considered. A main objective of the proposed methodology is to provide scientific evidence for better understanding of how future climate regimes might affect the interconnected CI during their lifespan and accounting for ageing, and how to assess the costeffectiveness of different adaptation measures. Additionally, an example in the flooding impact to Torbay in South West UK is presented.