Combination enzyme therapy for gastric digestion of dietary gluten in patients with celiac sprue

J Gass, MT Bethune, M Siegel, A Spencer, C Khosla - Gastroenterology, 2007 - Elsevier
… , is an inheritable autoimmune disease of the small intestine … The only accepted treatment
for celiac disease is a strict, … -contamination of foods, inadequate food labeling regulations, and …

Detoxification of gluten by means of enzymatic treatment

H Wieser, P Koehler - Journal of AOAC International, 2012 - academic.oup.com
Celiac disease (CD) is an inflammatory disease of the upper … enzymes; they permeate
the lymphatic tissue, are bound to … The enzymes derive from a naturally safe food source; no …

Highly efficient gluten degradation by lactobacilli and fungal proteases during food processing: new perspectives for celiac disease

CG Rizzello, M De Angelis, R Di Cagno… - Applied and …, 2007 - Am Soc Microbiol
… Presently, the only effective treatment for celiac disease is a … to intestinal brush border enzymes.
The pretreatment of … ELISA, in foods that have been processed by enzymatic procedures. …

The biochemical basis of celiac disease

H Wieser, P Koehler - Cereal Chemistry, 2008 - Wiley Online Library
Celiac disease (CD), also known as celiac sprue and glutensensitive enteropathy, is one
of the most frequent food … Rational design of combination enzyme therapy for celiac sprue. …

Gluten, celiac disease, and gluten intolerance and the impact of gluten minimization treatments with prolylendopeptidase on the measurement of gluten in beer

GJ Tanner, ML Colgrave, CA Howitt - Journal of the American …, 2014 - Taylor & Francis
… in food and beverages by destroying epitopes that are used to enumerate gluten peptides –
we ask, “does PEP treatment destroy celiac … in celiac disease—role of enzyme specificity and …

[HTML][HTML] Consumption of gluten with gluten-degrading enzyme by celiac patients: a pilot-study

GJ Tack, JMW Van de Water, MJ Bruins… - World journal of …, 2013 - ncbi.nlm.nih.gov
… METHODS: Patients with initial diagnosis of celiac disease as … gastrointestinal subcategory
of the celiac disease quality (CDQ) … The only currently available treatment for celiac disease

Digestive peptidases in Tenebrio molitor and possibility of use to treat celiac disease

EN Elpidina, IA Goptar - Entomological Research, 2007 - Wiley Online Library
… proteinases in the course of food digestion were similar. According to inhibitor analysis, the
… stomach; therefore, the enzyme presumably has great potential for celiac disease treatment. …

Degradation of coeliac disease-inducing rye secalin by germinating cereal enzymes: diminishing toxic effects in intestinal epithelial cells

SM Stenman, K Lindfors, JI Venäläinen… - Clinical & …, 2010 - academic.oup.com
… In future, these enzymes might be utilized as a novel medical treatment for coeliac
disease or in food processing in order to develop high-quality coeliac-safe food products. …

Next-generation therapies for celiac disease: The gluten-targeted approaches

M Ribeiro, FM Nunes, M Rodriguez-Quijano… - Trends in Food Science …, 2018 - Elsevier
treatment available. Compliance to the restrictive diet is demanding and new treatment strategies
for celiac disease … quantify gluten in food products is an enzyme-linked immunosorbent …

[HTML][HTML] Highly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease

D Stepniak, L Spaenij-Dekking… - American Journal …, 2006 - journals.physiology.org
… Because no animal model for celiac disease is available, an in … , and at food grade quality,
the enzyme appears to be a good … An effective enzymatic treatment for celiac disease requires …