Eupalitin induces apoptosis in prostate carcinoma cells through ROS generation and increase of caspase‐3 activity

S Kaleem, S Siddiqui, HH Siddiqui… - Cell biology …, 2016 - Wiley Online Library
Prostate cancer is the second most common malignancy in the human reproductive system.
Eupalitin is one of the O‐methylated flavonol‐exhibited enhanced cancer chemopreventive
agents. The current study highlights the structural determination of eupalitin and aims to
explore the antitumor activity of eupalitin in human prostate cancer cell (PC3) and its
underlying mechanism. Eupalitin structure was determined by using FTIR, 1H NMR, and
13C NMR. PC3 cells were treated with increasing concentrations of eupalitin, followed by …

Eupalitin induces apoptosis in prostate carcinoma cells through ROS generation and increase of caspase-3 activity.

SK Sarjeel Kaleem, SS Sahabjada Siddiqui… - 2016 - cabidigitallibrary.org
Prostate cancer is the second most common malignancy in the human reproductive system.
Eupalitin is one of the O-methylated flavonol-exhibited enhanced cancer chemopreventive
agents. The current study highlights the structural determination of eupalitin and aims to
explore the antitumor activity of eupalitin in human prostate cancer cell (PC3) and its
underlying mechanism. Eupalitin structure was determined by using FTIR, 1H NMR, and
13C NMR. PC3 cells were treated with increasing concentrations of eupalitin, followed by …
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