Evaluation of the immune response to interferon gamma release assay and tuberculin skin test among BCG vaccinated children in east of Egypt: a cross-sectional …
MR Beshir, AE Zidan, HF El-Saadny, RA Ramadan… - Medicine, 2016 - journals.lww.com
Abstract Bacille Calmette-Guérin vaccine (BCG) vaccination is used routinely in most of
countries, especially developing one. The efficacy of the BCG vaccination generally
decreases with time. The tuberculin skin test (TST) is a most popular diagnostic test for
suspicion of tuberculosis (TB) in children till now, but it has many false positives. The
interferon-gamma release assay (IGRA) is more specific than TST for detection of childhood
TB, as it is more specific to Mycobacterium tuberculosis.
countries, especially developing one. The efficacy of the BCG vaccination generally
decreases with time. The tuberculin skin test (TST) is a most popular diagnostic test for
suspicion of tuberculosis (TB) in children till now, but it has many false positives. The
interferon-gamma release assay (IGRA) is more specific than TST for detection of childhood
TB, as it is more specific to Mycobacterium tuberculosis.
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