Evaluation of vascular endothelial growth factor–A release from platelet-rich fibrin, platelet-rich fibrin matrix, and dental pulp at different time intervals

S Nagaraja, S Mathew, A Abraham… - Journal of …, 2020 - journals.lww.com
Background: Lack of collateral blood supply and the low compliance environment of pulp
makes its healing, a challenge. Vascular endothelial growth factor (VEGF) is a primary
angiogenic growth factor. Knowledge of dose and time-dependent expression of VEGF from
platelet concentrates, namely platelet-rich fibrin (PRF) and PRF matrix (PRFM), along with
vital pulp can aid in developing strategies to improve the outcome of vital pulp therapy and
regenerative procedures. Hence, the aim of this study was to compare VEGF kinetics of PRF …
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