Evolution of the quorum sensing regulon in cooperating populations of Pseudomonas aeruginosa

NE Smalley, AL Schaefer, KL Asfahl, C Perez… - MBio, 2022 - Am Soc Microbiol
… uses quorum sensing (QS) to activate expression of dozens of genes (the QS regulon). …
size and content of the QS regulon, we asked how the regulon might evolve during long-term P. …

Quorum sensing provides a molecular mechanism for evolution to tune and maintain investment in cooperation

EL Bruger, DJ Snyder, VS Cooper… - The ISME …, 2021 - academic.oup.com
regulon in V. campbellii consists of around 10% of the genome [29, 31]. Because regulons
… This architecture also means that the QS regulon includes genes relevant to both public and …

Bacterial quorum sensing and microbial community interactions

RG Abisado, S Benomar, JR Klaus, AA Dandekar… - MBio, 2018 - Am Soc Microbiol
regulons, and behavioral responses associated with quorum-… Studies of the role of quorum
sensing in cooperative and … question in evolutionary biology is how do cooperative systems …

Social evolution selects for redundancy in bacterial quorum sensing

E Even-Tov, S Omer Bendori, J Valastyan, X Ke… - PLoS …, 2016 - journals.plos.org
… about cell population density. Quorum sensing allows bacteria to synchronize their behaviors
and act as collectives. Often, quorum sensing controls cooperative behaviors that benefit …

Behavioral heterogeneity in quorum sensing can stabilize social cooperation in microbial populations

K Zhao, L Liu, X Chen, T Huang, L Du, J Lin, Y Yuan… - BMC biology, 2019 - Springer
… By monitoring the evolutionary dynamics of cooperative and cheating behaviors in bacterial
IPG, we find that bacterial social structure can be readily diverged by the strategy shift of …

A spatial model of the evolution of quorum sensing regulating bacteriocin production

T Czárán, RF Hoekstra - Behavioral Ecology, 2007 - academic.oup.com
… Like any form of cooperative behavior, quorum sensing (QS) in … the evolutionary stability
of QS as a regulatory mechanism of antibiotics production in a spatially structured population, …

Maximizing growth yield and dispersal via quorum sensing promotes cooperation in Vibrio bacteria

EL Bruger, CM Waters - Applied and environmental microbiology, 2018 - Am Soc Microbiol
evolved between signaling, cooperation, and other coregulated behaviors. Another important
distinction is that while these earlier examples primarily relied upon differences in growth …

Evolution of Quorum Sensing in Pseudomonas aeruginosa Can Occur via Loss of Function and Regulon Modulation

P Jayakumar, ART Figueiredo, R Kümmerli - Msystems, 2022 - Am Soc Microbiol
… QS mutants could arise and spread due to (i) disuse of the regulon, (ii) cheating on the
cooperative benefits of QS, or (iii) modulation of one or several of the three systems. Here, we …

Acyl-homoserine lactone quorum sensing: from evolution to application

M Schuster, D Joseph Sexton, SP Diggle… - Annual review of …, 2013 - annualreviews.org
… Each quorum-sensing regulon is shown as a distinct entity, but in reality there is overlapping
… Signal-blind cheats invade cooperating populations to a greater extent when the cost of …

Non-social adaptation defers a tragedy of the commons in Pseudomonas aeruginosa quorum sensing

KL Asfahl, J Walsh, K Gilbert, M Schuster - The ISME journal, 2015 - academic.oup.com
quorum sensing (QS), often coordinates other cooperative … the sustained cooperative growth
of the evolved population. … size of the lasR-controlled QS regulon and the difference in the …