[HTML][HTML] Ex vivo addition of fibrinogen concentrate improves the fibrin network structure in plasma samples taken during liver transplantation
DJ Groeneveld, J Adelmeijer, GCG Hugenholtz… - Journal of Thrombosis …, 2015 - Elsevier
Background Optimal hemostatic management during orthotopic liver transplantation (OLT)
remains a challenge. The cause of bleeding during OLT is multifactorial, and may include
hemostatic imbalance. Fibrinogen concentrates are increasingly being used to control
perioperative bleeding during OLT. However, administration is based on arbitrary thresholds
of fibrinogen levels. Importantly, studies on fibrin clot structure during OLT are lacking.
Objective We determined the hemostatic efficacy of fibrinogen concentrate in correcting the …
remains a challenge. The cause of bleeding during OLT is multifactorial, and may include
hemostatic imbalance. Fibrinogen concentrates are increasingly being used to control
perioperative bleeding during OLT. However, administration is based on arbitrary thresholds
of fibrinogen levels. Importantly, studies on fibrin clot structure during OLT are lacking.
Objective We determined the hemostatic efficacy of fibrinogen concentrate in correcting the …
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