Selectable markers constitute essential genetic tools in fungal transformation. Markers find
increased application with the availability of complete genome sequences of many
Aspergilli. Fungal selection markers may confer resistance to antibiotics or antimetabolites,
provide nutritional growth advantages or allow direct visual selection of transformed cells.
While many of them are already described for Aspergillus, additional markers continue to be
sought and developed. The choice of a marker depends on several considerations like the …

Aspergilli are a unique group of saprophytic filamentous fungi that dwell in wide spectrum of
habitat such as soil, decaying organic matter, and moist indoor environments. Enormous
nutritional flexibility underlies their successful lifestyle. The genus Aspergillus is gifted with
rich ability to secrete degradative enzymes, organic acids and secondary metabolites. These
fungi are capable of growth in a wide range of pH (between pH 2.0 and pH 11.0),
temperature (10–50 C) and high osmolarity (Kis-Papo et al. 2003). These endowments have …