In robotic rehabilitation a promising paradigm is assistance-as-needed. This is because it promotes patient active participation which is essential for neuro-rehabilitation. A model-based assistance-as-needed paradigm has been developed which utilizes a musculoskeletal model representing the subject to calculate their assistance needs. In this paper we experimentally evaluate this model-based paradigm to control an assistive robot and provide a subject with assistance-as-needed at the muscular level. A subject with impairments defined in specific muscle groups performs a number of upper limb tasks, whilst receiving assistance from a robotic exoskeleton. The paradigm is evaluated on its ability to provide assistance only as the subject needs, depending on the tasks being performed and the impairments defined. Results show that the model-based assistance-as-needed paradigm was relatively successful in providing assistance when it was needed.