[PDF][PDF] Experimental model of autoimmune myosin-induced myocardium injury
VI Bobyk, DV Ryabenko, OV Sergienko… - Biopolymers & …, 2007 - researchgate.net
VI Bobyk, DV Ryabenko, OV Sergienko, IV Trunina, OM Fedorkova, LM Morozova…
Biopolymers & Cell, 2007•researchgate.netExperimental model of autoimmune myosin-induced injury of BALB/c mouse myocardium,
similar to human dilated cardiomyopathy (DCM), has been developed. The immunisation by
myosin, purified from DCM-affected human heart initiated the following DCM-like myocardial
damage: myocytolysis, cardiosclerosis, thinning of left ventricular wall, changes in cardiac
actomyosin ATP-ase activity and increase of anti-myosin autoantibodies level.
similar to human dilated cardiomyopathy (DCM), has been developed. The immunisation by
myosin, purified from DCM-affected human heart initiated the following DCM-like myocardial
damage: myocytolysis, cardiosclerosis, thinning of left ventricular wall, changes in cardiac
actomyosin ATP-ase activity and increase of anti-myosin autoantibodies level.
Experimental model of autoimmune myosin-induced injury of BALB/c mouse myocardium, similar to human dilated cardiomyopathy (DCM), has been developed. The immunisation by myosin, purified from DCM-affected human heart initiated the following DCM-like myocardial damage: myocytolysis, cardiosclerosis, thinning of left ventricular wall, changes in cardiac actomyosin ATP-ase activity and increase of anti-myosin autoantibodies level.
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