Wireless technologies offer many advantages in communication between Internet of Things (IoT) devices, yet, it lacks in performance especially indoors where walls, metal, and other objects deteriorate their performance. LoRa is a new technology that may offer better indoor performance. In this article, we present and analyze LoRa's parameters, and aim to optimize them for use in a reinforced concrete building. Our experimental results show that increasing the spreading factor (SF) and coding rate (CR) increase the packet transmission duration, which has a detrimental effect on the packet reception ratio. Moreover, our main contribution is that we propose an optimized configuration that results in a higher packet reception ratio in an indoor environment.