This paper explores the relationship between spatial structure and spatial interaction at the intraurban level. To examine this relationship an experimental framework is designed based on the application of a doubly constrained entropy-type gravity model to journey-to-work data for twenty-four Canadian urban areas. The study demonstrates that distance-decay exponents are strongly influenced by geographic structure and the geometry of origins and destinations. As such, both the influence of map pattern and the friction of distance should be explicitly incorporated into spatial interaction models. The paper also explores the impact of city size and the nature of the economic base of the urban area upon distance-decay exponents.