Exploring the different environments effect of piperine via combined crystallographic, QM/MM and molecular dynamics simulation study
K Saravanan, M Sivanandam, G Hunday… - Journal of Molecular …, 2019 - Elsevier
Piperine is a pungent alkaloid, largely present in the skin of pepper. It is the most active
component of pepper and being used as a medicine in many Asian countries. The effect of
piperine on memory impairment and neurodegeneration in Alzheimer's disease model has
been investigated. In the present study, we aim to investigate the effect of piperine molecule
in different environments (crystal and active site of proteins) from crystallography, molecular
docking, QM/MM based charge density analysis and molecular dynamic simulation. The …
component of pepper and being used as a medicine in many Asian countries. The effect of
piperine on memory impairment and neurodegeneration in Alzheimer's disease model has
been investigated. In the present study, we aim to investigate the effect of piperine molecule
in different environments (crystal and active site of proteins) from crystallography, molecular
docking, QM/MM based charge density analysis and molecular dynamic simulation. The …
以上显示的是最相近的搜索结果。 查看全部搜索结果