Expression of antimicrobial peptides in diabetic foot ulcer
B Rivas-Santiago, V Trujillo, A Montoya… - Journal of …, 2012 - Elsevier
BACKGROUND: Foot ulcers are one of the main diabetes complications due to its high
frequency and difficulty of complete healing. There are several factors that participate in
diabetic ulcers development and limited information exists about the role of antimicrobial
peptides (AMP) in its pathogenesis. OBJECTIVE: The aim of this study was to analyze the
expression pattern of the main AMPs: Human Neutrophil Peptide (HNP)-1, Human β-
defensin (HBD)-1, HBD-2, HBD-3, HBD-4 and cathelicidin LL-37 in biopsies from diabetic …
frequency and difficulty of complete healing. There are several factors that participate in
diabetic ulcers development and limited information exists about the role of antimicrobial
peptides (AMP) in its pathogenesis. OBJECTIVE: The aim of this study was to analyze the
expression pattern of the main AMPs: Human Neutrophil Peptide (HNP)-1, Human β-
defensin (HBD)-1, HBD-2, HBD-3, HBD-4 and cathelicidin LL-37 in biopsies from diabetic …
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