Expression quantitative trait methylation analysis reveals methylomic associations with gene expression in childhood asthma
Background Nasal (airway) epithelial methylation profiles have been associated with
asthma, but the effects of such profiles on expression of distant cis-genes are largely
unknown. Research Question To identify genes whose expression is associated with
proximal and distal CpG probes (within 1 Mb), and to assess whether and how such genes
are differentially expressed in atopic asthma. Study Design and Methods Genome-wide
expression quantitative trait methylation (eQTM) analysis in nasal epithelium from Puerto …
asthma, but the effects of such profiles on expression of distant cis-genes are largely
unknown. Research Question To identify genes whose expression is associated with
proximal and distal CpG probes (within 1 Mb), and to assess whether and how such genes
are differentially expressed in atopic asthma. Study Design and Methods Genome-wide
expression quantitative trait methylation (eQTM) analysis in nasal epithelium from Puerto …
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