Extensive transcriptional regulation of chromatin modifiers during human neurodevelopment
Epigenetic changes, including histone modifications or chromatin remodeling are regulated
by a large number of human genes. We developed a strategy to study the coordinate
regulation of such genes, and to compare different cell populations or tissues. A set of 150
genes, comprising different classes of epigenetic modifiers was compiled. This new tool was
used initially to characterize changes during the differentiation of human embryonic stem
cells (hESC) to central nervous system neuroectoderm progenitors (NEP). qPCR analysis …
by a large number of human genes. We developed a strategy to study the coordinate
regulation of such genes, and to compare different cell populations or tissues. A set of 150
genes, comprising different classes of epigenetic modifiers was compiled. This new tool was
used initially to characterize changes during the differentiation of human embryonic stem
cells (hESC) to central nervous system neuroectoderm progenitors (NEP). qPCR analysis …
[PDF][PDF] Extensive Transcriptional Regulation of Chromatin Modifiers during Human
MK Weng, B Zimmer, D Pöltl, MP Broeg, V Ivanova - 2012 - academia.edu
Epigenetic changes, including histone modifications or chromatin remodeling are regulated
by a large number of human genes. We developed a strategy to study the coordinate
regulation of such genes, and to compare different cell populations or tissues. A set of 150
genes, comprising different classes of epigenetic modifiers was compiled. This new tool was
used initially to characterize changes during the differentiation of human embryonic stem
cells (hESC) to central nervous system neuroectoderm progenitors (NEP). qPCR analysis …
by a large number of human genes. We developed a strategy to study the coordinate
regulation of such genes, and to compare different cell populations or tissues. A set of 150
genes, comprising different classes of epigenetic modifiers was compiled. This new tool was
used initially to characterize changes during the differentiation of human embryonic stem
cells (hESC) to central nervous system neuroectoderm progenitors (NEP). qPCR analysis …
以上显示的是最相近的搜索结果。 查看全部搜索结果