Many endophenotypes, such as eye-movement characteristics [1] and brain structural changes,[2] are known in schizophrenia (SCZ). Eye movements serve as an output of cognitive processing and better performance has been associated with better social functioning in SCZ.[3] However, the neuroanatomical correlates of eye-movement abnormalities in SCZ are still unclear. The frontal eye fields are brain regions crucially involved in eye-movement control and functional changes in these areas have been linked with smooth pursuit changes in SCZ.[4] The frontal eye field is expected to be involved in the caudal middle frontal area in the Desikan-Killiany atlas.[5] However, we did not find significant correlations with the eye-movement measures after Bonferroni correction.[Extracted from the article]

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