Facile ecofriendly synthesis of monastrol and its structural isomers via biginelli reaction

M Oliverio, P Costanzo, M Nardi, I Rivalta… - ACS Sustainable …, 2014 - ACS Publications
green chemical methodologies for the organic synthesis, so our attention was attracted by the
reported methods for performing the Biginelli reaction … to perform the Biginelli reaction in a …

1, 3-Bis (carboxymethyl) imidazolium chloride as a sustainable, recyclable, and metal-free ionic catalyst for the Biginelli multicomponent reaction in neat condition

P Madivalappa Davanagere, B Maiti - ACS omega, 2021 - ACS Publications
synthesized the commercially available drug Monastrol by employing this methodology. The
new synthesis … Next, we performed the model Biginelli reaction by changing the mmol ratio …

A century-old one-pot multicomponent Biginelli reaction products still finds a niche in drug discoveries: Synthesis, mechanistic studies and diverse biological activities …

S Faizan, TF Roohi, RM Raju, Y Sivamani… - … of Molecular Structure, 2023 - Elsevier
… nine isomers including … Monastrol, and other major physiologically active dihydropyrimidines
2-(1H)-one/thione analogs. Despite the fact that the Biginelli reaction is regarded as a facile

[PDF][PDF] Síntesis de Monastrol y análogos, compuestos con potenciales actividades farmacológicas. Una revisión bibliográfica.

DP Quevedo Fajardo - 2018 - riull.ull.es
Facile ecofriendly synthesis of monastrol and its structural isomers via Biginelli reaction.
ACS Sustainable Chemistry & Engineering (2014), vol. 2, nº 5, 1228-1233. (34) Kumar Prajapti, …

Solvent-free Biginelli reactions catalyzed by hierarchical zeolite utilizing a ball mill technique: A green sustainable process

A Shahid, NS Ahmed, TS Saleh, SA Al-Thabaiti… - Catalysts, 2017 - mdpi.com
… is the two-step synthesis procedure, a … synthesize hierarchical ZSM-5 by post treatments
of commercial H-ZSM-5. We aim to improve its catalytic performance towards Biginelli reaction

Bio-catalysis in multicomponent reactions

ND Jumbam, W Masamba - Molecules, 2020 - mdpi.com
… Compared to standard organic synthesis wherein compounds are prepared individually and
reaction, Wang and his group developed the first enzyme-catalyzed Biginelli reaction using

Montmorillonite K10: An efficient organo-heterogeneous catalyst for synthesis of benzimidazole derivatives

S Bonacci, G Iriti, S Mancuso, P Novelli, R Paonessa… - Catalysts, 2020 - mdpi.com
… that do not follow the principles of green chemistry are problems for the pharmaceutical
industry. The organic synthesis of chemical structures that represent the starting point for …

Nano-ZrO2-Catalyzed Biginelli Reaction and the Synthesis of Bioactive Dihydropyrimidinones That Targets PPAR-γ in Human Breast Cancer Cells

SN Deveshegowda, JR Yang, Z Xi, O Nagaraja… - Catalysts, 2023 - mdpi.com
… a Biginelli reaction to synthesize bioactive DHPs using nano-… allows organic substrates and
reagents to selectively reacted to … , by using less hazardous reaction conditions, or by facile

Design, synthesis, and evaluation of donepezil-like compounds as AChE and BACE-1 inhibitors

P Costanzo, L Cariati, D Desiderio… - ACS medicinal …, 2016 - ACS Publications
… In conclusion, a sustainable multistep protocol for the synthesis of a set of traditional, as
well … tube assisted method for the synthesis of the indanone moieties and in a green US-assisted …

Topologically Driven Pore/Surface Engineering in a Recyclable Microporous Metal–Organic Vessel Decorated with Hydrogen-Bond Acceptors for Solvent-Free …

A Gogia, SK Mandal - ACS Applied Materials & Interfaces, 2022 - ACS Publications
… On the basis of results presented in this work, it is clear that (a) the Biginelli reaction occurs
… is observed through the Lewis acidic activation. Thus, the involvement of either its surface or …