Objective: To investigate the relation between outcomes of children with diabetic
ketoacidosis (DKA)-related cerebral edema and baseline clinical features and therapeutic
interventions for treatment of cerebral edema. Study design: All children≤ 18 years old with
DKA and cerebral edema (n= 61) were retrospectively identified from 10 pediatric centers
between 1982 and 1997. Demographic, biochemical, and therapeutic data were collected.
Ordinal logistic regression analysis was used to identify factors associated with the clinical …

Methods Eligible patients were 18 years of age or younger and had been examined at the
study centers between 1982 and 1997. Factors examined included baseline clinical
features, biochemical abnormalities at admission and during therapy, neurologic signs and
symptoms, therapies, and outcome. Results Sixty-one patients with cerebral edema met
study criteria; 36 (59%) survived with no persistent neurologic deficits, 8 (13%) survived with
mild or moderate persistent neurologic disabilities, 13 (21%) died, and 4 (7%) survived in a …