Factors associated with dyspnea in adult patients with sickle cell disease

C Delclaux, F Zerah-Lancner, D Bachir, A Habibi… - Chest, 2005 - Elsevier
Objective: The aim of this prospective study was to determine the cardiorespiratory factors
associated with dyspnea in patients with sickle cell SS-hemoglobin disease, with a specific
interest in lung vascular involvement. Measurements: Forty-nine patients (29 women and 20
men; mean [±SD] age: women, 29±6 years; men, 31±11 years) underwent direct evaluations
(Borg scale evaluation during a 6-min walk test) and indirect evaluations (modified Medical
Research Council [MRC] score) of their dyspnea, pulmonary function tests …
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