Family history of depression and neural reward sensitivity: Findings from the Adolescent Brain Cognitive Development Study
Background Previous studies have found that offspring of depressed parents exhibit
reduced striatal reward response to anticipating and receiving rewards, suggesting that this
may constitute a neurobiological risk marker for depression. The present study aimed to
assess whether maternal and paternal depression history have independent effects on
offspring reward processing and whether greater family history density of depression is
associated with increased blunting of striatal reward responses. Methods Data from the …
reduced striatal reward response to anticipating and receiving rewards, suggesting that this
may constitute a neurobiological risk marker for depression. The present study aimed to
assess whether maternal and paternal depression history have independent effects on
offspring reward processing and whether greater family history density of depression is
associated with increased blunting of striatal reward responses. Methods Data from the …
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