Fatty acid binding protein-4 is expressed in the mouse placental labyrinth, yet is dispensable for placental triglyceride accumulation and fetal growth
Abstract Introduction Fatty Acid Binding Protein-4 (FABP4) is a member of a family of FABP
proteins that regulate intracellular lipid trafficking in diverse tissues. We recently showed that
FABP4 regulates triglyceride accumulation in primary human trophoblasts. To assess the
function of placental FABP4 in vivo, we tested the hypothesis that FABP4 is expressed in the
murine placenta, and regulates placenta triglyceride accumulation. Methods C57Bl/6 wild
type or Fabp4-null mice were time-bred, and fetuses and placentas harvested at different …
proteins that regulate intracellular lipid trafficking in diverse tissues. We recently showed that
FABP4 regulates triglyceride accumulation in primary human trophoblasts. To assess the
function of placental FABP4 in vivo, we tested the hypothesis that FABP4 is expressed in the
murine placenta, and regulates placenta triglyceride accumulation. Methods C57Bl/6 wild
type or Fabp4-null mice were time-bred, and fetuses and placentas harvested at different …
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