Fiber molecular model of atelocollagen–small interfering RNA (siRNA) complex
DV Svintradze, GM Mrevlishvili - International journal of biological …, 2005 - Elsevier
DV Svintradze, GM Mrevlishvili
International journal of biological macromolecules, 2005•ElsevierPreviously we represented molecular model of collagen triple helix–DNA double helix
complex [GM Mrevlishvili, DV Svintradze, Int. J. Macromol. 36 (2005) 324–326; GM
Mrevlishvili, DV Svintradze, Int. J. Macromol. 35 (2005) 243–245]. We also proved that
during the complex formation hydration of triple helix destroys and forms new water bridges
maintaining the complex nano-structure. In this paper we demonstrate that small interfering
RNA binds to atelocollagen directly to form siRNA–atelocollagen fiber complex.
complex [GM Mrevlishvili, DV Svintradze, Int. J. Macromol. 36 (2005) 324–326; GM
Mrevlishvili, DV Svintradze, Int. J. Macromol. 35 (2005) 243–245]. We also proved that
during the complex formation hydration of triple helix destroys and forms new water bridges
maintaining the complex nano-structure. In this paper we demonstrate that small interfering
RNA binds to atelocollagen directly to form siRNA–atelocollagen fiber complex.
Previously we represented molecular model of collagen triple helix–DNA double helix complex [G.M. Mrevlishvili, D.V. Svintradze, Int. J. Macromol. 36 (2005) 324–326; G.M. Mrevlishvili, D.V. Svintradze, Int. J. Macromol. 35 (2005) 243–245]. We also proved that during the complex formation hydration of triple helix destroys and forms new water bridges maintaining the complex nano-structure. In this paper we demonstrate that small interfering RNA binds to atelocollagen directly to form siRNA–atelocollagen fiber complex.
Elsevier
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