Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer

J Tchou, PJ Zhang, Y Bi, C Satija, R Marjumdar… - Human pathology, 2013 - Elsevier
Fibroblast activation protein (FAP) has long been known to be expressed in the stroma of
breast cancer. However, very little is known if the magnitude of FAP expression within the
stroma may have a prognostic value and reflect the heterogeneous biology of the tumor cell.
An earlier study had suggested that stromal FAP expression in breast cancer was inversely
proportional to prognosis. We, therefore, hypothesized that stromal FAP expression may
correlate with clinicopathologic variables and may serve as an adjunct prognostic factor in …
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