MV Dieci, M Arnedos, F Andre, JC Soria - Cancer discovery, 2013 - AACR
The fibroblastgrowthfactor/fibroblastgrowthfactorreceptor (FGF/FGFR) signaling pathway plays a fundamental role in many physiologic processes, including embryogenesis, adult …
G Marseglia, A Lodola, M Mor… - Expert Opinion on …, 2019 - Taylor & Francis
… : fibroblastgrowthfactorreceptors (FGFRs) are a family of tyrosine-kinase receptors whose … safer and more selective covalent inhibitors might supersede reversible inhibitors in specific …
S Dai, Z Zhou, Z Chen, G Xu, Y Chen - Cells, 2019 - mdpi.com
… Increasing evidence indicates that aberrant Fibroblastgrowthfactorreceptors (FGFR)signaling plays a crucial role in tumorigenesis and progression. Now, small molecule inhibitors …
OE Pardo, J Latigo, RE Jeffery, E Nye, R Poulsom… - Cancer research, 2009 - AACR
… that fibroblastgrowthfactor-2 induces proliferation and … fibroblastgrowthfactorreceptor (FGFR) inhibitor PD173074 blocks H-510 and H-69 SCLC proliferation and clonogenic growth in …
F Manetti, F Corelli, M Botta - Current pharmaceutical design, 2000 - ingentaconnect.com
… of the fibroblastgrowthfactorreceptor 1 (FGFR1) … fibroblastgrowthfactorreceptor. Exogenous FGF added to myogenic cultures has a mitogenic effect promoting myoblast proliferation …
… Fibroblastgrowthfactorreceptor 1 to 4 inhibitors are now approved by the US Food and … fibroblastgrowthfactorreceptor (FGFR)–altered bladder and biliary cancers. As FGFR inhibition …
M Katoh - Nature reviews Clinical oncology, 2019 - nature.com
… , and the benefits of FGFR inhibitors have been demonstrated in … the clinical experience with FGFR inhibitors to date, and … FGFR inhibitors in combination regimens with other agents. …
J Hsu, JH Francis, S Ahmad - Survey of Ophthalmology, 2024 - Elsevier
… Fibroblastgrowthfactorreceptor (FGFR) inhibitors are an emerging class of small molecule targeted cancer drugs with … While ocular adverse events from FGFR inhibitors are reported in …
M Rusnati, M Presta - Current pharmaceutical design, 2007 - ingentaconnect.com
… Fibroblastgrowthfactor/fibroblastgrowthfactorreceptor system in angiogenesis. Cytokine GrowthFactor Rev 2005; … A truncated form of fibroblastgrowthfactorreceptor 1 inhibits signal …