Fibroblast growth factor receptor inhibitors

S Kumar BVS, L Narasu, R Gundla… - Current …, 2013 - ingentaconnect.com
… Abstract: Fibroblast growth factor receptors (FGFRs) play an important role in embryonic …
Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth

Fibroblast growth factor receptor inhibitors as a cancer treatment: from a biologic rationale to medical perspectives

MV Dieci, M Arnedos, F Andre, JC Soria - Cancer discovery, 2013 - AACR
The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) signaling pathway
plays a fundamental role in many physiologic processes, including embryogenesis, adult …

Fibroblast growth factor receptor inhibitors: patent review (2015–2019)

G Marseglia, A Lodola, M Mor… - Expert Opinion on …, 2019 - Taylor & Francis
… : fibroblast growth factor receptors (FGFRs) are a family of tyrosine-kinase receptors whose
… safer and more selective covalent inhibitors might supersede reversible inhibitors in specific …

Fibroblast growth factor receptors (FGFRs): structures and small molecule inhibitors

S Dai, Z Zhou, Z Chen, G Xu, Y Chen - Cells, 2019 - mdpi.com
… Increasing evidence indicates that aberrant Fibroblast growth factor receptors (FGFR)signaling
plays a crucial role in tumorigenesis and progression. Now, small molecule inhibitors

The Fibroblast Growth Factor Receptor Inhibitor PD173074 Blocks Small Cell Lung Cancer Growth In vitro and In vivo

OE Pardo, J Latigo, RE Jeffery, E Nye, R Poulsom… - Cancer research, 2009 - AACR
… that fibroblast growth factor-2 induces proliferation and … fibroblast growth factor receptor
(FGFR) inhibitor PD173074 blocks H-510 and H-69 SCLC proliferation and clonogenic growth in …

Fibroblast growth factors and their inhibitors

F Manetti, F Corelli, M Botta - Current pharmaceutical design, 2000 - ingentaconnect.com
… of the fibroblast growth factor receptor 1 (FGFR1) … fibroblast growth factor receptor. Exogenous
FGF added to myogenic cultures has a mitogenic effect promoting myoblast proliferation

Clinical and morphologic characteristics of fibroblast growth factor receptor inhibitor–associated retinopathy

JH Francis, JJ Harding, AM Schram… - JAMA …, 2021 - jamanetwork.com
Fibroblast growth factor receptor 1 to 4 inhibitors are now approved by the US Food and …
fibroblast growth factor receptor (FGFR)–altered bladder and biliary cancers. As FGFR inhibition

Fibroblast growth factor receptors as treatment targets in clinical oncology

M Katoh - Nature reviews Clinical oncology, 2019 - nature.com
… , and the benefits of FGFR inhibitors have been demonstrated in … the clinical experience
with FGFR inhibitors to date, and … FGFR inhibitors in combination regimens with other agents. …

Ocular toxicities of fibroblast growth factor receptor inhibitors: a review

J Hsu, JH Francis, S Ahmad - Survey of Ophthalmology, 2024 - Elsevier
Fibroblast growth factor receptor (FGFR) inhibitors are an emerging class of small molecule
targeted cancer drugs with … While ocular adverse events from FGFR inhibitors are reported in …

Fibroblast growth factors/fibroblast growth factor receptors as targets for the development of anti-angiogenesis strategies

M Rusnati, M Presta - Current pharmaceutical design, 2007 - ingentaconnect.com
Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. Cytokine
Growth Factor Rev 2005; … A truncated form of fibroblast growth factor receptor 1 inhibits signal …