BACKGROUND: We report the first human experience with an endoscopic duodenal-jejunal
bypass sleeve (DJBS) in a community hospital. METHODS: The DJBS is a 60-cm sleeve
anchored in the duodenum to create a duodenal-jejunal bypass. In a 12-patient prospective,
open-label, single-center, 12-week study, the device was endoscopically implanted, left in
situ, and retrieved. The study included 5 men and 7 women, with a mean body mass index of
43 kg/m2. Of the 12 patients, 4 had type 2 diabetes. The primary endpoints were the …

Methods The DJBS is a 61cm sleeve anchored in the duodenum creating a duodenal-
jejunal bypass. In a 12-patient prospective, open label, single center, 12-week safety study,
the device was endoscopically implanted, left in situ and retrieved. The study included 5
males and 7 females, mean BMI= 43 kg/m 2. Four patients had type 2 diabetes (T2DM). The
primary endpoints were incidence/severity of adverse events. Secondary outcomes
included% excess weight loss (% EWL) and changes in co-morbid status. Results The DJBS …