Flavonoids of Herba Epimedii regulate osteogenesis of human mesenchymal stem cells through BMP and Wnt/β-catenin signaling pathway

J Zhang, G Li, C Chan, C Meng, MC Lin, Y Chen… - Molecular and Cellular …, 2010 - Elsevier
Herba Epimedii is one of the most … the flavonoids of Herba Epimedii (HEF) have shown to
promote the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells

Total flavonoids of Herba Epimedii improves osteogenesis and inhibits osteoclastogenesis of human mesenchymal stem cells

JF Zhang, G Li, CL Meng, Q Dong, CY Chan, ML He… - Phytomedicine, 2009 - Elsevier
… the effect of flavonoids of Herba Epimedii (HEF) on osteogenesis in human MSCs. … Osteoclast
differentiation is a core regulation that could balance bone formation and bone response. …

Flavonoids of Herba Epimedii stimulate osteogenic differentiation and suppress adipogenic differentiation of primary mesenchymal stem cells via estrogen receptor …

D Zhang, L Liu, Z Jia, X Yao, M Yang - Pharmaceutical Biology, 2016 - Taylor & Francis
Herba Epimedii in regulating the cross-talk between osteogenic and adipogenic differentiation
of mesenchymal stem cellsflavonoids of Herba Epimedii (HETF) on the osteogenesis and …

Therapeutic potential of Chinese medicinal herbs stimulating osteogenic differentiation of bone marrow-derived mesenchymal stem cells in osteoporosis

H Wang, K Shan, Y Li, S Wu, C Zhou, S Tao… - Frontiers in …, 2024 - frontiersin.org
During bone formation, BMSCs are regulated by various … Moreover, total flavonoids of
Drynariae rhizome can upregulate … This study also indicated that Epimedii folium and Ligustri …

Potential Role of Herbal Remedies on Mesenchymal Stem Cells: An Overview of New Therapeutic Strategies for Osteoporosis

Y Liu, C Li, M Deng, Y Ma, Z Jin… - Journal of Organoid and …, 2024 - jobs.isoor.org
Flavonoids of herba epimedii stimulate osteogenic … of primary mesenchymal stem cells
via estrogen receptor pathway… bone mesenchymal stem cells regulating osteogenesis by …

Modern approach to study the osteoprotective effects of Herba Epimedii

S Mok - 2007 - theses.lib.polyu.edu.hk
… Effect of total extract, total flavonoids and non-flavonoids of Herba Epimedii on serum …
Osteoblasts are originated from mesenchymal stromal cells and are responsible for bone formation

Herba epimedii flavonoids suppress osteoclastic differentiation and bone resorption by inducing G2/M arrest and apoptosis

D Zhang, J Zhang, C Fong, X Yao, M Yang - Biochimie, 2012 - Elsevier
… found to improve osteogenesis and inhibit osteoclastogenesis of human mesenchymal stem
cells [8]… In conclusion, Herba epimedii flavonoids could regulate the formation and activity of …

Explorating the mechanism of Epimedii folium-Rhizoma drynariae herbal pair promoted bone defects healing through network pharmacology and experimental …

SS Lei, XW Huang, LZ Li, XP Wang, Y Zhang… - Journal of …, 2024 - Elsevier
… EDP promoted bone formation in bone defects using network … of bone marrow mesenchymal
stem cells (BMSCs). … signaling pathways, but also flavonoids such as berberine, naringin, …

[HTML][HTML] Absorption and utilisation of epimedin C and icariin from Epimedii herba, and the regulatory mechanism via the BMP2/Runx2 signalling pathway

X Huang, X Wang, Y Zhang, L Shen, N Wang… - Biomedicine & …, 2019 - Elsevier
… of the two flavonoids and their osteogenesis effect in LPS-induced osteoblasts. In the present
study, a previously established quantitative method of flavonoid glycosides by pipette tip …

Flavonoids of Herba epimedii and bone metabolism in experimental ovarian deficiency

MS Wong, Y Zhang - Nutrition and Diet in Menopause, 2013 - Springer
… models, such as osteoblast, osteoclast, and mesenchymal stem cell, are also widely applied
… was associated with a remarkable up regulation of bone formation rate both as a reference …