Fluoromycobacteriophages Can Detect Viable Mycobacterium tuberculosis and Determine Phenotypic Rifampicin Resistance in 3–5 Days From Sputum Collection

L Rondón, E Urdániz, C Latini, F Payaslian… - Frontiers in …, 2018 - frontiersin.org
The World Health Organization (WHO) estimates that 40% of tuberculosis (TB) cases are not
diagnosed and treated correctly. Even though there are several diagnostic tests available in
the market, rapid, easy, inexpensive detection, and drug susceptibility testing (DST) of
Mycobacterium tuberculosis is still of critical importance specially in low and middle-income
countries with high incidence of the disease. In this work, we have developed a microscopy-
based methodology using the reporter mycobacteriophage mCherrybomb ϕ for detection of …

Fluoromycobacteriophages can detect viable Mycobacterium tuberculosis and determine phenotypic rifampicin resistance in 3-5 days from sputum collection

L Rondon Salazar, E Urdániz, C Latini, FP Payaslian… - 2018 - ri.conicet.gov.ar
The World Health Organization (WHO) estimates that 40% of tuberculosis (TB) cases are not
diagnosed and treated correctly. Even though there are several diagnostic tests available in
the market, rapid, easy, inexpensive detection, and drug susceptibility testing (DST) of
Mycobacterium tuberculosis is still of critical importance specially in low and middle-income
countries with high incidence of the disease. In this work, we have developed a microscopy-
based methodology using the reporter mycobacteriophage mCherrybombΦ for detection of …
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