The aim of this review was to focus on food safety in relation to pesticide and veterinary drug residues and mycotoxins in meat and meat products. The impact of these consumers awareness is a large concern for the meat industry. In order to be more prepared, the consumer strive to have more complete information on the sources of inputs in their products, because consumers are becoming more worried about this. Residues in meat and their products are generally classified as naturally present, caused by man and arise secondarily. In the past, most contamination of meat resulted from natural toxicants. However, usage of synthetic chemicals for regular house-hold and agricultural practices while benefiting society has also provided new sources of potential contamination. The levels of pesticide residues are now over alarming situation in certain countries. Drug residues in meat are relatively uncommon whereas, aflatoxin or ochratoxin are rarely found. Residues from secondary residues also occur less frequently. This study reviews the causes of residues in meat, types of residues found, their detection methods, incidences and their regulation with emphasis on public health risk and their assessment.