Formation of DNA: RNA Hybrid G‐Quadruplex in Bacterial Cells and Its Dominance over the Intramolecular DNA G‐Quadruplex in Mediating Transcription …
DNA with four guanine tracts can fold into G‐quadruplexes that are targets of transcription
regulation. We recently found that hybrid DNA: RNA G‐quadruplexes (HQs) can form during
in vitro transcription. However, it is unclear whether they can form in cells. Evidence is
presented supporting their formation in plasmids in bacterial cells. The formation of the HQs
is indicated by a unique pattern of prematurely terminated transcripts under two conditions
where the RNA transcripts do or do not participate in G‐quadruplex assembly and further …
regulation. We recently found that hybrid DNA: RNA G‐quadruplexes (HQs) can form during
in vitro transcription. However, it is unclear whether they can form in cells. Evidence is
presented supporting their formation in plasmids in bacterial cells. The formation of the HQs
is indicated by a unique pattern of prematurely terminated transcripts under two conditions
where the RNA transcripts do or do not participate in G‐quadruplex assembly and further …
[PDF][PDF] Formation of DNA: RNA Hybrid G-Quadruplex in Bacterial Cells and Its Dominance over the Intramolecular DNA G-Quadruplex in Mediating Transcription …
吴壬乙， 郑克威， 张佳宇， 郝玉华， 谭铮 - 2015 - library.ioz.ac.cn
DNA with four guanine tracts can fold into G-quadruplexes that are targets of transcription
regulation. We recently found that hybrid DNA: RNA G-quadruplexes (HQs) can form during
in vitro transcription. However, it is unclear whether they can form in cells. Evidence is
presented supporting their formation in plasmids in bacterial cells. The formation of the HQs
is indicated by a unique pattern of prematurely terminated transcripts under two conditions
where the RNA transcripts do or do not participate in G-quadruplex assembly and further …
regulation. We recently found that hybrid DNA: RNA G-quadruplexes (HQs) can form during
in vitro transcription. However, it is unclear whether they can form in cells. Evidence is
presented supporting their formation in plasmids in bacterial cells. The formation of the HQs
is indicated by a unique pattern of prematurely terminated transcripts under two conditions
where the RNA transcripts do or do not participate in G-quadruplex assembly and further …
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