Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review

A Mermer, T Keles, Y Sirin - Bioorganic Chemistry, 2021 - Elsevier
… In this study, many compounds were designed to obtain best antiviral potency by
changing substituents, functional group and linker against the target virus. In this context, N-…

Synthesis and applications of nitrogen-containing heterocycles as antiviral agents

TN Tran, M Henary - Molecules, 2022 - mdpi.com
… [24] discovered compounds to target the chymotrypsin-like protease (CL pro ), which plays
a vital role in cleaving polyproteins to produce functional proteins directly involved in viral

Sulfonamides with heterocyclic periphery as antiviral agents

MY Moskalik - Molecules, 2022 - mdpi.com
… require complex functionalization of substituents [… heterocycles are the part of a large
number of drugs of synthetic and natural origin [28,29]. Combining sulfonamide and N-heterocyclic

Recent advances in nitrogen-containing heterocyclic scaffolds as antiviral agents

Kanupriya, RK Mittal, V Sharma, T Biswas… - Medicinal …, 2024 - benthamdirect.com
… thorough analysis of nitrogen-containing heterocycles, focusing on their … antiviral drugs. To
better understand how nitrogen-containing heterocycles can be used to create antiviral drugs, …

Recent advances on heterocyclic compounds with antiviral properties

A De, S Sarkar, A Majee - Chemistry of Heterocyclic Compounds, 2021 - Springer
heterocyclic compounds and their applications in antiviral treatment. Highly potent and specific
antiviral drugs … on the chemical functionalization of some heterocyclic moieties to improve …

Antiviral activities of pyridine fused and pyridine containing heterocycles, a review (from 2000 to 2020)

SR Alizadeh, MA Ebrahimzadeh - Mini Reviews in Medicinal …, 2021 - ingentaconnect.com
… We believe that pyridine derivatives can be used as promising antiviral agents and more …
functional at the B3LYP/6-31G (d,p) level. The relationship of the difference of the antiviral effect …

N-Heterocycles as Promising Antiviral Agents: A Comprehensive Overview

G Ahmad, M Sohail, M Bilal, N Rasool, MU Qamar… - Molecules, 2024 - mdpi.com
… -heterocycles as antiviral agents to the reader under one topic. First, five-membered N-heterocycles
were … Several aryl and alkyl functionalized ribavirin derivatives were synthesized and …

Recent developed nitrogen/sulfur heterocyclic compounds with marked and selective antiviral activities (microreview)

F Mutalabisin, M Ghafarikhaligh… - Current Organic …, 2023 - benthamdirect.com
… The resistance to the existence of antiviral drugs on the market is the main threat to human
health… The transformation of the carboxylic acid moiety to the ester functional group showed a …

Seeking heterocyclic scaffolds as antivirals against dengue virus

S De, B Aamna, R Sahu, S Parida, SK Behera… - European Journal of …, 2022 - Elsevier
… of numerous potential heterocyclic scaffolds as antiviral drug candidates for the … heterocyclic
moiety having the highest binding affinity of −141.595 kJ/mol. The use of Density functional

The design and synthesis of novel N-heterocyclic compounds, and their evaluation of anti-cancer and anti-viral activity

V More - 2014 - elea.unisa.it
heterocycleantiviral agents: arbidol is an indole compound launched in the Russian
Federation for the prophylaxis and treatment of influenza A and B and other acute respiratory viral