Molds are the chief pathogens of stored sweet potato and as such cause huge post-harvest and economic losses to tuber farmers in Nigeria. This research was aimed at isolating and identifying molds associated with post-harvest loss of Ipomoea batatas L Lam. The spoilage molds identified were Aspergillus fumigatus, Aspergillus niger, and Rhizopus stolonifer. These isolates were subjected to pathogenicity tests using fresh healthy tubers in order to confirm their ability to elicit same spoilage symptoms in healthy tubers. Six healthy tubers were used for this study. Dry rot was recorded in all the tubers. Percentage Weight loss of tubers were monitored and values of 1.04±0.44, 0.45±0.46 and 0.75±0.24 with P˃ 0.1 were recorded. Whereas values of 98.29±0.35, 98.06±1.00 and 98.73±0.01 with P˃ 0.1 were recorded for the percentage rot severity.