thiazole ring system with mercaptoalkanoic acids were investigated. Antimycobacterial activities of compounds thus obtained were evaluated against Mycobacterium tuberculosis H37RV using rifampine as standard.
Abstract
Reaction of aldehyde-hydrazones or semicarbazones bearing an imidazo [2, 1-b][1, 3] thiazole ring system with mercaptoalkanoic acids were investigated. Antimycobacterial activities of compounds thus obtained were evaluated against Mycobacterium tuberculosis H37RV using rifampine as standard.