[HTML][HTML] Galacto-oligosaccharides supplementation in prefrail older and healthy adults increased faecal bifidobacteria, but did not impact immune function and …
E Wilms, R An, A Smolinska, Y Stevens, AR Weseler… - Clinical Nutrition, 2021 - Elsevier
Background & aims Ageing is associated with an increased risk of frailty, intestinal
microbiota perturbations, immunosenescence and oxidative stress. Prebiotics such as
galacto-oligosaccharides (GOS) may ameliorate these ageing-related alterations. We aimed
to compare the faecal microbiota composition, metabolite production, immune and oxidative
stress markers in prefrail elderly and younger adults, and investigate the effects of GOS
supplementation in both groups. Methods In a randomised controlled cross-over study, 20 …
microbiota perturbations, immunosenescence and oxidative stress. Prebiotics such as
galacto-oligosaccharides (GOS) may ameliorate these ageing-related alterations. We aimed
to compare the faecal microbiota composition, metabolite production, immune and oxidative
stress markers in prefrail elderly and younger adults, and investigate the effects of GOS
supplementation in both groups. Methods In a randomised controlled cross-over study, 20 …